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Bronchiectasis

Suspect this in any patient with increased ICP, especially if there is fever or increased TLC. It may follow ear, sinus, dental, or periodontal infection; skull fracture; congenital heart disease; endocarditis; bronchiectasis. It may also occur in the absence of systemic signs of inflammation.

Investigations

  • Sputum culture
  • CXR: Cystic shadows, thickened bronchial walls (tramline and ring shadows)
  • HRCT chest
  • Spirometry
  • Bronchoscopy to locate site of haemoptysis, exclude obstruction and obtain samples for culture.
  • Other tests:
    • Serum immunoglobulins
    • Cystic Fibrosis sweat test
    • Aspergillus precipitins or skin-prick test RAST and total IgE.

Treatment

  • Chest physiotherapy
  • Mucolytics
  • Antibiotics:
    • According to culture and sensitivity
    • Pseudomonas will require either oral ciprofloxacin or suitable IV antibiotics
    • long-term antibiotics (may be nebulized), If ≥3 exacerbations a year
  • Bronchodilators (eg nebulized salbutamol)
  • Corticosteroids (eg prednisolone) and itraconazole for Allergic bronchopulmonary aspergillosis (ABPA)
  • Surgery may be indicated in localized disease or to control severe haemoptysis.

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